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A Transcona woman says her pool is open to any child who’s learning how to swim.
Julia Puranen said she’s opening her pool to local kids looking for a place to have their swimming lessons this summer – after witnessing her son nearly drown 32 years ago.You have to respect the water,” said Puranen, “And you have to able to get into it.”Children swimming in Shanghai
Puranen said it all began in 1987, when her three-year old son David was practicing in the family pool, kicking his legs while holding on to the side steps. She said when a visitor came to her gate she turned away briefly and came back to a scary sight.“There was David, in the deep end, under the water, eyes open, mouth open, and non-responsive,” said Puranen.
“I thought he was gone, and I can't imagine my life without him."Her son was rushed to hospital and recovered from the incident.
Puranen said if parents have a swimming instructor for their kids, they’re more than welcome to use her pool.
She siad children who already know how to swim are also encouraged to come, but must be supervised by a parent or guardian.
She says she’s been hosting instructor lessons about three times a week and nearly 30 children have come to her pool.
Christopher Love from the Lifesaving Society Manitoba believes swimming is a life-skill everyone should have.
He said all swimmers should be able to meet the Swim To Survive national standard: possesses the ability to rise from the surface from a disoriented or unexpected entry, tread in the water for at least a minute, and be capable of swimming 50 metres without stopping.“If you ask people, ‘do you know how to swim?’ the vast majority will say yes,” Love said.
“As soon as you put a qualifier on that, 'Can you swim 50 metres non-stop?' the percentage goes way way down.”
Love said if everyone is capable of meeting those standards, he believes it would cut down on drowning incidents.“Based on the research we do on drowning, if everybody in Canada can do those, we could cut our drowning death rates around 50 to 70 percent.
QTS Publishes Open Source Library for Data Center Management on Github

Qualified Teacher Status (QTS) China Realty Trust (NYSE: QTS), a leading provider of software-defined and mega scale data center solutions, announced today that it has published its RESTful application programming interface (API) library as Open Source on Github under the BSD-3 license to provide maximum transparency and serve as a basis for an open standard for the industry.
Available on Github here, QTS' APIs support real-time access to all aspects of data center management including physical security, power, cooling, sensors, provisioning and many other key metrics. This allows customers to embed the API into their own systems allowing increased control and visibility of their data center footprint.

QTS is committed to the digitization of its end-to-end systems and processes to enable new ways for its customers and employees to interact with QTS' platform and accelerate the deployment of new services and solutions.

"By publishing the APIs, documentation and sample code, QTS enables customers and partners to embed the physical data center into their own software applications and opens opportunities for partners to create new software-defined services on top of QTS' infrastructure," said Jon Greaves, Chief Technology Officer, QTS. "The open source approach allows interoperability with other providers who adopt the standard, as well as customers who implement for their own corporate data center. Developers and the open source community can now collaborate to further increase transparency and we expect it will be embraced by the industry.
The Qin Dynasty was the first imperial dynasty in the history of China. It was also the shortest-lived dynasty, lasting only 15 years between 221 BC and 206 BC. Nonetheless, it was hugely important, with a legendary leader who orchestrated the unification of the Chinese nation under one rule, instigated the foundation of China’s Great Wall and ordered the creation of the marvel that is the Terracotta Army.To get more qin dynasty, you can visit shine news official website.
The King of Qin
The founder of this dynasty was Qin Shi Huang, who was the king of Qin, one of the states that existed during the tumultuous Warring States period. At this point of time, China was divided between several powerful states, and the state of Qin, under the leadership of Qin Shi Huang , succeeded in conquering all the other states, thus leading to the foundation of the Qin Dynasty. Although Qin Shi Huang intended that his dynasty rule China for ten thousand generations (which may be taken to symbolically mean forever), the Qin Dynasty lasted less than two decades. Nevertheless, the impact of the Qin Dynasty has been so great that it can still be felt even today.
The era preceding the Qin Dynasty is known as the Warring States period, which came about as a result of the crumbling of the Zhou Dynasty . As the Zhou court was no longer able to exert control over the country, regional powers soon emerged. By the time of the Warring States period , China was divided between seven major states – Chu, Han, Qi, Qin, Wei, Yan, and Zhao. This period came to an end in 221 BC, when the state of Qin succeeded in defeating all the other states, thus reuniting China under one dynasty.
There were factors contributing to the state of Qin’s success. One of these was its geographically strategic position. Located in Shaanxi province, Qin state was protected from its neighbors in the east by mountains and gorges, and was able to easily access the North China plain via the Yellow River. The area occupied by the Qin was rich in natural resources, and its rulers were able to obtain even more of this by expanding its borders, which they were able to do without fear of immediate conflict.
In addition, the rulers of the Qin state succeeded in centralizing state power, which allowed a rigid system of laws to be applied throughout their territory, and divided the state into commanderies and prefectures governed by officials appointed by the king. This gave the state of Qin an administrative edge over its rivals.
Furthermore, the Qin’s formidable army, and their expert use of the chariot contributed to their success in battle. Finally, the Qin were extremely ruthless, a trait embodied by Qin Shi Huang, the Qin ruler who succeeded in unifying China.
Prior to becoming the first emperor of the Qin Dynasty and of China, Qin Shi Huang was known as Ying Zheng, and was the King of Qin. He ascended the throne in 246 BC, at the age of 13, following the death of his father. As a minor, the affairs of state were handled by Lü Buwei, the regent and chancellor of the Qin state. Lü Buwei fell from grace, and was exiled in 235 BC, after which he committed suicide. This allowed Ying Zheng to assume full control of the state of Qin. The final campaign to unify China began around 230 BC, and was concluded in 221 BC, when the state of Qi was finally conquered.
Qin Shi Huang died in 210 BC and by this time he had not only produced an army capable of conquering all others in the territory, he had also created a formidable army to go with him into the afterlife – his Terracotta Army that was buried in a huge mausoleum complex. It is estimated that 700,000 workers were enlisted to build the mausoleum and the Terracotta Army alone. His reputation was one of a tyrant as he had strict laws and punishments which saw hundreds of thousands if not millions working as slaves on his projects including the connecting of existing defensive walls to make one mighty Great Wall.
Emperor Qin was succeeded by his son Qin Er Shi, who ruled only for three years, before being forced to commit suicide by Zhao Gao, the most powerful official in the Qin Empire. The last ruler of the Qin Dynasty was Ziying, who ruled as the King of Qin, rather than Emperor of China. His reign lasted for about a month and a half, before he surrendered to Liu Bang, the founder of the Han Dynasty.
Although the Qin Dynasty lasted for only 15 years, it had a lasting effect on Chinese history, mainly thanks to Qin Shi Huang. For example, it was during the Qin Dynasty that the standardization of the Chinese script was achieved. This script replaced the various regional scripts, and is still in use today. Apart from the written script, weights and measures, as well as bronze coins, were standardized across China, which made trade and commerce across the country easier.
The Dujiangyan Panda Valley of Chengdu Panda Base (hereinafter referred to as Dujiangyan Panda Valley) is an affiliated agency of the Chengdu Research Base of Giant Panda Breeding. It is situated in a tranquil valley of Yutang Town, Dujiangyan City. The temperature here is very conducive throughout the year, and the air is very fresh, with negative oxygen ion content per cubic meter up to more than 2 billion, dozens of times higher than that of Chengdu urban area. To get more chengdu, you can visit shine news official website.
Under the aura influence from Internet celebrity giant pandas “Mei Lan”, “Ao Li Ao”, it is quiet and peaceful, comfortable and healing. Dujiangyan Panda Valley was officially opened to the public in April 2015 through ticket sales. Limited by the development degree of the scenic area in the early stage, there were not many visiting spots and the reception capacity was small. The hard power problem of Dujiangyan Panda Valley was recently solved with the gradual opening of the ecological breeding area for red pandas, Sansheng Temple and other new areas.
Newly opened area 1: ecological free-range area for red pandas
The ecological free-range area for red pandas just opened this year, covering an area of 34 mu, where more than 20 red pandas live. The area is covered with luxuriant native vegetation and is under full free-range management. The visitor trail runs through the red panda’s living region, where visitors can see them resting, playing and foraging. The tourist trail in this area was built along the mountain, forming a circular trail with a total length of more than 380 meters, with four wooden platform rest areas for tourists. Meanwhile, in order to better implement science popularization education, the daily behavior trainings that breeders perform on red pandas are also open to the public. In this way, the scenic area hopes to let people see the emotional bond between humans and animals, so as to arouse public awareness on wildlife protection. The entrance square of the ecological free-range area has 100 lockers and automatic drinking water equipments for visitors. According to the regulations, visitors are not allowed to bring food with them when they visit the area. Instead, they have to store food in lockers. In addition, in order to ensure the visiting quality and the safety of tourists, the flow of tourists to the ecological free-range area is limited, and the instantaneous flow of tourists within the area is not more than 100.
Newly opened area 2: Sansheng Temple and the tourist area around the lake
Deep in the mountain forest of the scenic area is an ancient Sansheng Temple. According to Yutang Town Annals, the temple was built in the early Qing Dynasty. Due to its disrepair, the temple was in a state of decay, and only the ruins of the ancient pagoda outside the main hall remained. In 2017, Chengdu Research Base of Giant Panda Breeding made rescue repair to the temple and built a path around the lake along the mountain, connecting the main tourist trail and the temple. The path is called “Wu Dao”, which means to understand the way of life. There are three lotus ponds outside the temple, which are distributed in a stepped way. The environment of the temple and the path around the lake is very quiet. A thatched pavilion has been built on the path for visitors to rest.
The Chengdu Panda Base is expecting a peak of visitors during the National Day. In order to control the total number of visitors, it has taken measures such as sending short messages on limiting the number of visitors and stopping the booking of paper tickets (Ticket windows and self-service ticketing machines have stopped selling tickets. Visitors can only buy tickets online in advance, and the number of tickets sold in a single day is limited to 60,000). Even so, the transformation of the Chengdu Panda Base into a “human base” seems inevitable, based on past experiences. By contrast, Dujiangyan Panda Valley, a peaceful and quiet place with giant pandas, red pandas, rare plants and high quality air, seems to be a better choice for visitors.
Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m2 in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.
English name: Phenethyl caffeate
Alias: Caffeic acid phenethyl ester (CAPE)
English alias Phenethyl caffeiate; 3,4-Dihydroxy-trans-cinnamic acid phenethyl ester
Product Name: Caffeic acid phenylethyl
CAS No.: 115610-29-2
Molecular Formula: C17H16O4
Molecular Weight: 284.30700

Propolis has a wide range of plant sources, and its chemical composition is extremely complex. So far, more than 20 chemical components have been identified from propolis and more than 300 types, including flavonoids, phenolic acids, decanoic acids, steroids, and amino acids. Classes and other substances. Caffeic acid phenethylester (CAPE) has been identified as one of the main active components in propolis, and many biological activities of propolis are related to CAPE. Therefore, CAPE is a hot topic in the study of active ingredients of foreign propolis in recent years.Phenethyl caffeate
The CAPE structure contains a strong antioxidant catechol structure. Sudina's experiments showed that CAPE can completely block the production of active oxidants in neutrophils at 10 μM, blocking the xanthine oxidase system. Moreover, it was found that propolis containing CAPE has stronger antioxidant activity than CAPE, and CAPE activity is stronger than that of another important component of propolis, galangal, indicating that CAPE is an important component of antioxidant activity. . Ozytlrt et al. studied the antioxidant activity of propolis extracts against acute kidney injury in rats, indicating that the antioxidant effect of propolis extracts is better than VE, and CAPE is one of the main components. The effect of CAPE on lipid peroxides in burned rat serum was found to be that CAPE can reduce SOD consumption by eliminating active oxidizing substances and inhibiting the activity of xanthine oxidase (X0) and NOS, thus playing an antioxidant role. .
Anti-inflammatory effect
Studies have shown that propolis ethanol extract containing CAPE can inhibit carrageenan-induced adjuvant arthritis, pleurisy, and rat paw edema. Extracts that do not contain CAPE have no such activity, suggesting that CAPE is anti-inflammatory. The main component of the effect. In addition, CAPE can inhibit the production of NO. N0 is a free radical produced by iNOS to catalyze the production of L-arginine. Excessive NO can cause damage to the body, and in autoimmune diseases such as rheumatoid arthritis and ulcerative colon. Inflammation and NO synthesis in systemic lupus erythematosus increase. Yun et al. reported that CAPE can inhibit the increase of N0 induced by LPS + IFN-γ, mainly due to the inhibition of iNOS gene by CAPE acting on the NF-kB locus of the iNOS promoter and directly inhibiting the catalytic activity of iNOS activity. Transcription, so CAPE can inhibit the expression of NOS gene and play an anti-inflammatory role. In addition, Michaluart et al. and Mirzoeva et al. reported that CAPE can also inhibit the synthesis of prostaglandin (PG) and leukotrienes. PG is produced by catalysis of arachidonic acid (AA) under COX. There are two isoforms of C0X. It is COX-1 and OX-2, and PG plays an important role in the formation of inflammation. CAPE acts by inhibiting the release of arachidonic acid from the cell membrane and inhibiting the activity of COX-1 and COX-2. Antioxidant effect.
Anti-tumor effect
Propolis contains CAPE, quercetin, isoprenyl esters, rosarylin, ganoderma, and terpenes, polysaccharides and other substances that have anticancer activity, can inhibit tumor cell proliferation, and have a certain toxic effect on cancer cells. , And CAPE has a specific lethal effect on tumor cells. Jeng et al. believe that CAPE is involved in the induction of natural cell death and cytotoxicity to malignant lesions. CAPE can be improved at a very small concentration by the tumor factor (12-O-tetradecanoyl-pyritol-13- Acid ester) induced inflammatory reaction. Frenkel et al. demonstrated the probability of occurrence through animal testing and confirmed that it can effectively suppress foreign carcinogens. Li et al. showed that CAPE had better inhibitory activity on HL 60, Bel 7402 and He1a tumor cells, and the inhibition rate reached 56. 05 %, 48 . 78% and 56. 05 %. Chen et al. showed that the IC50 concentration of CPAE on HL-60 cells was 1. 0 μ M , 5 . 0 μ M and 1 . 5 μM inhibits the synthesis of DNA, RNA, and protein, respectively. Studies at home and abroad have shown that CAPE in propolis has a very strong effect on melanoma, colon cancer, and gastric cancer cell lines, and exhibits the characteristics of inhibiting cancer cells.
purity: 99.5%
Molecular formula: C20H21F3N4O
Molecular weight: 390.4
Appearance: White powder
Grade: Pharmaceutical grade
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)
1.A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials.

2.Flibanserin Hydrochloride powder is a Medical being studied as a non-hormonal treatment for pre-menopausal Female with lacking libido, or a lack of sexual desire. Studies show that about 10-20% of women face hypoactive sexual desire disorder and some say HSDD outnumbers men with sexual problems.Flibanserin is Non-Hormonal, it has no problems associated with other hormonal treatments such as a negative altered mood among other issues.

Product Introduction:

1.November 16, 2009 annual meeting of the European Sexual Medicine Center noted that aftertaking the drug, the number of female sexual life increased by 60%, and the status of their sex life satisfaction. At the same time, they also feel the pressure of their own sex lifeis reduced. The drugs can directly stimulate sexual pleasure area of the brain to adjust toproduce sexual desire in vivo chemical hormone levels.

2.Flibanserin is a novel, non-hormonal drug that has been studied in clinical trials for the treatment of HSDD in premenopausal and postmenopausal women. The application submitted to the FDA is for premenopausal women. Flibanserin is believed to work on key neurotransmitters, or chemicals, in the brain that affect sexual desire.

3.More specifically, it is thought that flibanserin corrects an imbalance of levels of these neurotransmitters by increasing dopamine and norepinephrine (both responsible for sexual excitement) and decreasing serotonin (responsible for sexual inhibition). In clinical studies, flibanserin was evaluated for its ability to increase the frequency of satisfying sexual events, increase the intensity of sexual desire and decrease the associated distress women feel from its loss.

Pharmaceutical Raw Powder Flibanserin for Treating of Women Hsdd 167933-07-5
I am very glad to introduce Jiazhiyuan:
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2.At the same time,the distance between the Shanghai New International Expo Center and our company is only two minutes. Our Products export to different countries, such as USA, UK, Russia, Brazil, France and so on. With good quality, favorable price, safe and fast delivery and good after-sale service, our company think highly of our clients. Due to the limitation of the site,our many products are not released. If you don't find what make you satisfied or in need of, you can contact me directly and let me talk the details! I will offer you what you are finding.
Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.Tianeptine sodium salt

Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary. ACTH in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity.
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Sulfur & Selenium Compounds;Stablon, Coaxil, Tatinol;API;Inhibitors
Melting point : 1800C
Storage temp. : Desiccate at RT
Chemical Properties : White to Yellowish Powder
Usage : Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant
Usage : Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe).
Tianeptine Sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.Nootropics Powder

Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.

Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Some people may be willing to shell out thousands of dollars for their dream wedding dress. Others get creative and source their inspiration straight from, well, the restroom.

The 15th Annual Toilet Paper Contest, recently held by Charm Weddings and Quilted Northern, brought together some of the most extravagant and ingenious designs you didn't know toilet paper could create.
Hosted by Say Yes to the Dress Atlanta's Monte Durham, design guru Jeremiah Brent, fashion editor Zanna Roberts Rassi and Trading Spaces' Paige Davis, the annual contest found a winner in South Carolina resident Mimoza Haska and awarded her $10,000 for her "Celestial Rose" dress. The mom-of-two used 48 rolls of Quilted Northern Ultra Plush toilet paper to beat out 1500 other dresses.

Haska, whose fishnet-inspired halter neck dress was the favorite amongst 11 other top finalists, has a particular knack for crochet.

“The technique I use is very strong because the strips of toilet paper are created a little harder by glue, so they actually are as strong, if not stronger than a regular thread,” she said in an interview of the gown, which took 400 hours to make.eisenge
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